Enhanced Medicarpin Biosynthesis via Synthetic Biology in Saccharomyces cerevisiae
Medicarpin, a potent bioactive compound found in plants like Sophora japonica and Glycyrrhiza species, exhibits diverse medicinal properties. Despite limited…
Yeast Glucan Particles (YGPs): Pioneering Oral Targeted Drug Delivery for Macrophage-Related Diseases
Yeast Glucan Particles (YGPs), emerging drug carriers, exhibit specific uptake by macrophages, aiding targeted imaging and drug delivery to inflammation…
hnRNPU Regulation in Multiple Myeloma Sensitivity to Selinexor: Implications for Patient Stratification
Selinexor, a novel inhibitor for multiple myeloma (MM), faces limited research on resistance. Heterogeneous nuclear ribonucleoprotein U (hnRNPU) was identified…
Poleward Expansion of Turkey Vultures (Cathartes aura): Insights from a Species Distribution Model and Future Projections
Understanding the implications of global change, our study forecasts the poleward expansion of Turkey Vulture (Cathartes aura) distribution. Analyzing eBird…
Multi-Omics Approach for Short-Term COVID-19 Progression Prediction in ICU Patients
The study developed a multi-omics approach to predict short-term COVID-19 progression in ICU patients. Analyzing data from 32 SARS-CoV-2-infected patients,…
Genomic Insights for Wheat: Linkage and Association Mapping Identify Regions for Yield and Drought Tolerance Traits
This study utilized combined linkage analysis and association mapping in wheat to identify genomic regions associated with both yield and…
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cGAS-STING Saga: Navigating the Intricacies of Cardiovascular Resilience
The cyclic cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS)-stimulator of interferon genes (STING) pathway is important in innate…
Soybean Flowering: Genes and Markers for Temperature Response
This soybean study uncovered 101 Quantitative Trait Nucleotides (QTNs) associated with flowering responses to photo-thermal conditions. Three candidate genes—Glyma.08G302500 (GmHY5),…