Pioneering phase 2 clinical trial for glioblastoma delivers initial results. While no survival breakthroughs yet, this groundbreaking adaptive platform trial brings hope for efficient therapy identification.
Remnants of incomplete or abnormal cell division, such as micronuclei and aneuploidy, could contribute to the spread of cancer. When cells divide incorrectly, they may produce genetic material that is extruded into micronuclei, which can lead to genomic instability. This instability can result in genetic mutations, potentially promoting tumor growth and metastasis. Understanding these processes […]
Researchers developed a gel-based system by embedding nanoparticles loaded with cancer drugs within a gelatinous matrix. This innovative approach enhances drug delivery to solid tumors. The gel is injected directly into the tumor site, allowing sustained and controlled release of the medication over time. The nanoparticles gradually release the drugs, targeting the tumor while minimizing […]
Scientists piece together DNA repair pathways associated with breast, ovarian, and prostate cancers by conducting comprehensive studies on genetic mutations. They analyze patient samples and identify specific genetic alterations or mutations prevalent in these cancers. Through advanced sequencing techniques, they map out the pathways involved in DNA repair mechanisms. By understanding how these pathways […]
